C₂₈H₄₀O₇

Base Information

• Chemical Name: C₂₈H₄₀O₇
• CAS No.: 814920-14-4
• Molecular Formula: C₂₈H₄₀O₇
• Molecular Weight: 488.621

Synonyms:C₂₈H₄₀O₇

Chemical Property of C₂₈H₄₀O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₄₀O₇

There total 27 articles about C₂₈H₄₀O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C28H38O6 (814920-13-3) → C28H40O7 (814920-14-4)

Guidance literature:

C₂₈H₃₈O₆; With bis(cyclohexanyl)borane; In tetrahydrofuran; at 0 ℃; for 0.333333h;

With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/jo048681u

Reference yield:

(1S,3R,7R,8S,9R,10S,11S)-9-Benzyloxymethyl-10-hydroxymethyl-11-methyl-7-trimethylsilanyloxy-4-oxa-tricyclo[5.3.1.03,8]undecan-5-one (312923-90-3) → C28H40O7 (814920-14-4)

Guidance literature:

Multi-step reaction with 26 steps

1.1: 29 percent / diacetoxyiodobenzene; iodine / CH₂Cl₂ / 0.83 h / 0 °C / Irradiation

2.1: 86 percent / i-Pr₂NEt / CH₂Cl₂ / 10 h / 20 °C

3.1: O₃ / CH₂Cl₂ / 0.25 h / -78 °C

3.2: 83 percent / PPh₃ / CH₂Cl₂ / -78 - 20 °C

4.1: Zn(BH₄)2 / diethyl ether / 0.5 h / 0 °C

5.1: tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C

6.1: 2.25 g / PPTS / acetone / 14 h / 20 °C

7.1: LiHMDS; HMPA / tetrahydrofuran / 1.5 h / -78 °C

7.2: 86 percent / tetrahydrofuran / 0.92 h / -78 - -40 °C

8.1: O₃ / CH₂Cl₂ / 0.08 h / -78 °C

8.2: triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

9.1: 197 mg / NaBH₄ / CH₂Cl₂; methanol / 0.08 h / 20 °C

10.1: 97 percent / n-Bu₃P / tetrahydrofuran / 1.67 h / -78 - 20 °C

11.1: 252 mg / H₂O₂ / tetrahydrofuran / 12 h / 20 °C

12.1: 335 mg / LiAlH₄ / dioxane / 0.02 h / Heating

13.1: 345 mg / Et₃N; DMAP / CH₂Cl₂ / 1.17 h / 20 °C

14.1: 93 percent / 4-methylmorpholine N-oxide / TPAP / acetonitrile / 1 h / 20 °C

15.1: O₃ / CH₂Cl₂ / 0.67 h / -78 °C

15.2: 88 percent / triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

16.1: 86 percent / SmI₂; HMPA / tetrahydrofuran / 0.75 h / -40 - 0 °C

17.1: 87 percent / DMAP / tetrahydrofuran / 6 h / 20 °C

18.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.67 h / 20 °C

19.1: 98 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.58 h / 20 °C

20.1: 90 percent / NaBH₄; CeCl₃*7H₂O / methanol / 0.25 h / 0 °C

21.1: 77 percent / zinc chloride / CH₂Cl₂ / 0.75 h

22.1: 45 percent / (TMS)3SiH; AIBN / benzene / 0.33 h / Heating

23.1: 91 percent / cesium fluoride / dimethylformamide / 46 h / 130 °C

24.1: 91 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.92 h / 20 °C

25.1: n-BuLi / tetrahydrofuran; hexane / 0.42 h / 20 °C

25.2: 92 percent / tetrahydrofuran; hexane / 0 - 20 °C

26.1: dicyclohexylborane / tetrahydrofuran / 0.33 h / 0 °C

26.2: 92 percent / H₂O₂; NaOH / tetrahydrofuran / 0 - 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; samarium diiodide; cerium(III) chloride; zinc(II) tetrahydroborate; 2,2'-azobis(isobutyronitrile); tributylphosphine; [bis(acetoxy)iodo]benzene; tris-(trimethylsilyl)silane; bis(cyclohexanyl)borane; tetrabutyl ammonium fluoride; dihydrogen peroxide; iodine; pyridinium p-toluenesulfonate; Dess-Martin periodane; ozone; 4-methylmorpholine N-oxide; triethylamine; N-ethyl-N,N-diisopropylamine; cesium fluoride; zinc(II) chloride; lithium hexamethyldisilazane; tetrapropylammonium perruthennate; In tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; acetonitrile; benzene; 11.1: Grieco olefination / 19.1: Dess-Martin oxidation / 24.1: Dess-Martin oxidation / 25.2: Wittig reaction;

DOI:10.1021/jo048681u

Reference yield:

(1S,3R,7S,8S,9R,10R,11R)-9-Benzyloxymethyl-7,11-dihydroxy-10-(2-trimethylsilanyl-ethoxymethoxymethyl)-4-oxa-tricyclo[5.3.1.03,8]undecan-5-one → C28H40O7 (814920-14-4)

Guidance literature:

Multi-step reaction with 21 steps

1.1: 2.25 g / PPTS / acetone / 14 h / 20 °C

2.1: LiHMDS; HMPA / tetrahydrofuran / 1.5 h / -78 °C

2.2: 86 percent / tetrahydrofuran / 0.92 h / -78 - -40 °C

3.1: O₃ / CH₂Cl₂ / 0.08 h / -78 °C

3.2: triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

4.1: 197 mg / NaBH₄ / CH₂Cl₂; methanol / 0.08 h / 20 °C

5.1: 97 percent / n-Bu₃P / tetrahydrofuran / 1.67 h / -78 - 20 °C

6.1: 252 mg / H₂O₂ / tetrahydrofuran / 12 h / 20 °C

7.1: 335 mg / LiAlH₄ / dioxane / 0.02 h / Heating

8.1: 345 mg / Et₃N; DMAP / CH₂Cl₂ / 1.17 h / 20 °C

9.1: 93 percent / 4-methylmorpholine N-oxide / TPAP / acetonitrile / 1 h / 20 °C

10.1: O₃ / CH₂Cl₂ / 0.67 h / -78 °C

10.2: 88 percent / triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

11.1: 86 percent / SmI₂; HMPA / tetrahydrofuran / 0.75 h / -40 - 0 °C

12.1: 87 percent / DMAP / tetrahydrofuran / 6 h / 20 °C

13.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.67 h / 20 °C

14.1: 98 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.58 h / 20 °C

15.1: 90 percent / NaBH₄; CeCl₃*7H₂O / methanol / 0.25 h / 0 °C

16.1: 77 percent / zinc chloride / CH₂Cl₂ / 0.75 h

17.1: 45 percent / (TMS)3SiH; AIBN / benzene / 0.33 h / Heating

18.1: 91 percent / cesium fluoride / dimethylformamide / 46 h / 130 °C

19.1: 91 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.92 h / 20 °C

20.1: n-BuLi / tetrahydrofuran; hexane / 0.42 h / 20 °C

20.2: 92 percent / tetrahydrofuran; hexane / 0 - 20 °C

21.1: dicyclohexylborane / tetrahydrofuran / 0.33 h / 0 °C

21.2: 92 percent / H₂O₂; NaOH / tetrahydrofuran / 0 - 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; samarium diiodide; cerium(III) chloride; 2,2'-azobis(isobutyronitrile); tributylphosphine; tris-(trimethylsilyl)silane; bis(cyclohexanyl)borane; tetrabutyl ammonium fluoride; dihydrogen peroxide; pyridinium p-toluenesulfonate; Dess-Martin periodane; ozone; 4-methylmorpholine N-oxide; triethylamine; cesium fluoride; zinc(II) chloride; lithium hexamethyldisilazane; tetrapropylammonium perruthennate; In tetrahydrofuran; 1,4-dioxane; methanol; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; acetonitrile; benzene; 6.1: Grieco olefination / 14.1: Dess-Martin oxidation / 19.1: Dess-Martin oxidation / 20.2: Wittig reaction;

DOI:10.1021/jo048681u

upstream raw materials:

C₂₈H₃₈O₆

C₂₇H₃₆O₇

C₂₇H₃₈O₇

C₂₈H₄₂O₇Si

Downstream raw materials:

C₄₅H₇₂O₇Si₂

C₄₈H₇₄O₈Si₂

C₄₉H₇₆O₉Si₂

C₄₈H₇₆O₈Si₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 814920-14-4 C₂₈H₄₀O₇

Send

Send

Metric Ton KG G Pound L ML

Send

Send