2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite

Base Information

• Chemical Name: 2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite
• CAS No.: 334024-21-4
• Molecular Formula: C₁₁H₁₂O₅S
• Molecular Weight: 256.279
• Mol file: 334024-21-4.mol

Synonyms:2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite

Chemical Property of 2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite

There total 1 articles about 2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(2R,4S,5R)-2-phenyl-5-hydroxy-1,3-dioxane-4-methanol (117122-84-6) → 2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite (334024-21-4)

Guidance literature:

With thionyl chloride; triethylamine; In dichloromethane;

DOI:10.1021/jo001444g

Reference yield: 95.0%

2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite (334024-21-4) → 2,4-O-benzylidene-D-erythritol-1,3-cyclic-sulfate (302579-06-2)

Guidance literature:

With ruthenium trichloride; sodium periodate; In tetrachloromethane; water; acetonitrile; at 20 ℃;

DOI:10.1021/jo001444g

Reference yield:

2,4-O-benzylidene-D-erythritol-1,3-cyclic sulfite (334024-21-4) → 2,3,5-tri-O-benzyl-1,4-dideoxy-1,4-[[(2R,3R)-2,4-O-benzylidene-3-(sulfooxy)butyl]-episulfoniumylidene]-L-arabinitol inner salt

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / NaIO₄; RuCl₃*H₂O / acetonitrile; CCl₄; H₂O / 20 °C

2: 40 percent / K₂CO₃ / acetone / 75 °C

With ruthenium trichloride; sodium periodate; potassium carbonate; In tetrachloromethane; water; acetone; acetonitrile;

DOI:10.1021/jo001444g

upstream raw materials:

(2R,4S,5R)-2-phenyl-5-hydroxy-1,3-dioxane-4-methanol

Downstream raw materials:

2,4-O-benzylidene-D-erythritol-1,3-cyclic-sulfate