2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

Base Information

Chemical Name:2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin
CAS No.:118225-65-3
Molecular Formula:C₁₉H₁₉N₃O₂S
Molecular Weight:353.445
Hs Code.:

Synonyms:2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

Suppliers and Price of 2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

There total 15 articles about 2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2-Methylthio-4-phenyl-6-pyrrolidino-1,3-thiazinium-perchlorat

: 105-56-6
ethyl 2-cyanoacetate

: 118225-65-3
2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

Guidance literature:: With triethylamine; In acetic anhydride; acetic acid; for 4h; Heating;
DOI:10.1007/BF00810427

Reference yield:

: 10562-42-2
3,3-dichloro-1-phenyl-propenone

: 118225-65-3
2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / methanol; acetic acid / 2 h / Heating

2: 85 percent / methanol / 0.5 h / Heating

3: 78 percent / acetic acid / 0.25 h / Heating

4: 71 percent / 2) 70percent HClO₄/glacial acetic acid / benzene / 0.25 h / Heating

5: 87 percent / NEt₃ / acetic acid; acetic anhydride / 4 h / Heating

With perchloric acid; acetic acid; triethylamine; In methanol; acetic anhydride; acetic acid; benzene;
DOI:10.1007/BF00810427

Reference yield:

: 97309-67-6
4-Phenyl-2-pyrrolidin-1-yl-[1,3]thiazine-6-thione

: 118225-65-3
2-(Cyano-ethoxycarbonyl-methyliden)-4-phenyl-6-pyrrolidino-2H-1,3-thiazin

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / methanol / 0.5 h / Heating

2: 68 percent / acetic acid / 0.25 h / Heating

3: 71 percent / 2) 70percent HClO₄/glacial acetic acid / benzene / 0.25 h / Heating

4: 87 percent / NEt₃ / acetic acid; acetic anhydride / 4 h / Heating

With perchloric acid; acetic acid; triethylamine; In methanol; acetic anhydride; acetic acid; benzene;
DOI:10.1007/BF00810427