(5-Chloro-2-methylphenyl)hydrazine hydrochloride

Base Information

• Chemical Name: (5-Chloro-2-methylphenyl)hydrazine hydrochloride
• CAS No.: 5446-17-3
• Molecular Formula: C7H9ClN2
• Molecular Weight: 193.076
• Hs Code.: 2928009090
• DSSTox Substance ID: DTXSID50526967
• NSC Number: 17184
• Mol file: 5446-17-3.mol

Synonyms:5446-17-3;(5-CHLORO-2-METHYLPHENYL)HYDRAZINE HYDROCHLORIDE;1-(5-chloro-2-methylphenyl)hydrazine hydrochloride;(5-chloro-2-methylphenyl)hydrazine;hydrochloride;(5-Chloro-2-methylphenyl)hydrazine HCl;SCHEMBL403976;DTXSID50526967;NSC17184;5-chloro-2-methylphenylhydrazine HCl;MFCD04038837;NSC-17184;AKOS005143656;DS-13356;CS-0153561;C75556;EN300-7367878;A913737;(5-Chloro-2-methyl-phenyl)-hydrazine;A1-00564;(5-CHLORO-2-METHYLPHENYL)HYDRAZINEHYDROCHLORIDE;(5-Chloro-2-methylphenyl)hydrazine--hydrogen chloride (1/1)

Chemical Property of (5-Chloro-2-methylphenyl)hydrazine hydrochloride

Chemical Property:

• Vapor Pressure: 0.0179mmHg at 25°C
• Boiling Point: 253.8°Cat760mmHg
• Flash Point: 107.3°C
• PSA: 38.05000
• Density: 1.26g/cm³
• LogP: 3.50930
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 192.0221037
• Heavy Atom Count: 11
• Complexity: 108

Purity/Quality:

99% ^*data from raw suppliers

5-Chloro-2-methylphenylhydrazinehydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1)Cl)NN.Cl

Technology Process of (5-Chloro-2-methylphenyl)hydrazine hydrochloride

There total 2 articles about (5-Chloro-2-methylphenyl)hydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

5-chloro-2-methyl-benzenamine (95-79-4) → 5-chloro-2-methylphenylhydrazine hydrochloride (5446-17-3)

Guidance literature:

5-chloro-2-methyl-benzenamine; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 2h; Inert atmosphere;

With tin(II) chloride dihdyrate; In water; at 0 ℃; for 0.75h; Inert atmosphere;

Reference yield:

→ 5-chloro-2-methylphenylhydrazine hydrochloride (5446-17-3)

Guidance literature:

With hydrogenchloride; tin(ll) chloride;

DOI:10.1021/ja01603a040

Reference yield:

3-Aminocrotononitrile (1118-61-2) + 5-chloro-2-methylphenylhydrazine hydrochloride (5446-17-3) → 1-(5-chloro-2-methylphenyl)-3-methyl-1H-pyrazol-5-amine (1224944-69-7)

Guidance literature:

With hydrogenchloride; In ethanol; at 80 ℃; for 16h; Inert atmosphere;

upstream raw materials:

5-chloro-2-methyl-benzenamine

Downstream raw materials:

2-(4-chloro-2-methyl-phenyl)-5-methyl-2H-pyrazol-3-ylamine

1-(5-chloro-2-methylphenyl)-3-methyl-1H-pyrazol-5-amine

4-chloro-3,3,7-trimethyl-2-(1-phenyl-1H-pyrazol-4-yl)-3Hindole

4-chloro-2-(1-(4-chlorophenyl)-1H-pyrazol-4-yl)-3,3,7-trimethyl-3H-indole

Refernces