Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate

Base Information

Chemical Name:Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate
CAS No.:1069051-17-7
Molecular Formula:C₂₈H₂₅F₂NO₃
Molecular Weight:461.508
Hs Code.:

Synonyms:Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate

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Technology Process of Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate

There total 1 articles about Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1069048-07-2
ethyl (2E)-3-[3-(2-phenylethyl)-1H-indol-5-yl]-2-propenoate

: 5905-69-1
1-bromo-4-(difluoromethoxy)benzene

: 1069051-17-7
Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate

Guidance literature:: With potassium phosphate; palladium diacetate; johnphos; In acetic acid butyl ester; at 120 ℃; for 12h;

Reference yield:

: 1069051-17-7
Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate

: 1069051-20-2
(2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoic acid

Guidance literature:: Ethyl (2E)-3-{1-[4-(difluoromethoxy)phenyl]-3-(2-phenylethyl)-1H-indol-5-yl}propenoate; With water; sodium hydroxide; In tetrahydrofuran; ethanol; at 20 ℃;

With hydrogenchloride; In tetrahydrofuran; ethanol; water;