9-hydroxymethyl-10-carbamoylacridan

Base Information

• Chemical Name: 9-hydroxymethyl-10-carbamoylacridan
• CAS No.: 68011-71-2
• Molecular Formula: C15H14N2O2
• Molecular Weight: 254.288
• Mol file: 68011-71-2.mol

Synonyms:9-(hydroxymethyl)-10-carbamoylacridan;

Chemical Property of 9-hydroxymethyl-10-carbamoylacridan

Chemical Property:

• Vapor Pressure: 8.99E-12mmHg at 25°C
• Boiling Point: 523.2°C at 760 mmHg
• Flash Point: 270.2°C
• PSA: 68.25000
• Density: 1.38g/cm³
• LogP: 1.93460
• Storage Temp.: 2-8°C

Purity/Quality:

98.5% ^*data from raw suppliers

9-Hydroxymethyl-10-carbamoylacridan ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Carbamazepine Carbamazepine impurity.

Technology Process of 9-hydroxymethyl-10-carbamoylacridan

There total 1 articles about 9-hydroxymethyl-10-carbamoylacridan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbamazepine 10,11-epoxide (36507-30-9) → 9-Hydroxymethyl-10-carbamoylacridan (68011-71-2)

Guidance literature:

Multi-step reaction with 2 steps

1: BF₃*Et₂O / CH₂Cl₂ / 0.5 h / Ambient temperature

2: NaBH₄ / ethanol / 2 h / Ambient temperature

With sodium tetrahydroborate; boron trifluoride diethyl etherate; In ethanol; dichloromethane;

DOI:10.1021/jm00388a004

upstream raw materials:

carbamazepine 10,11-epoxide

Refernces