(RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

Base Information

Chemical Name:(RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester
CAS No.:1560797-65-0
Molecular Formula:C₃₁H₄₃ClN₂O₃
Molecular Weight:527.147
Hs Code.:

Synonyms:(RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

Suppliers and Price of (RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

Chemical Property:

Purity/Quality:: 98% HPLC ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

There total 3 articles about (RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 122368-54-1,210095-55-9
4-[(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidine

: 1560797-83-2
D-menthyl-4-chlorobutanoate

: 1560797-65-0
(RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

Guidance literature:: With potassium carbonate; sodium iodide; In acetonitrile; at 80 ℃; for 15h; Large scale;

Reference yield:

: 5382-16-1
4-HYDROXYPIPERIDINE

: 1560797-65-0
(RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 1 h / -70 °C / Large scale

1.2: 20 °C / Large scale

2.1: 5 h / 130 °C / Large scale

2.2: 15 h / 80 °C / Large scale

3.1: sodium iodide; potassium carbonate / acetonitrile / 15 h / 80 °C / Large scale

With potassium carbonate; triethylamine; sodium iodide; In dichloromethane; acetonitrile;

Reference yield:

: 4045-22-1
N-acetyl-4-hydroxypiperidine

: 1560797-65-0
(RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: 5 h / 130 °C / Large scale

1.2: 15 h / 80 °C / Large scale

2.1: sodium iodide; potassium carbonate / acetonitrile / 15 h / 80 °C / Large scale

With potassium carbonate; sodium iodide; In acetonitrile;