(S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

Base Information

Chemical Name:(S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester
CAS No.:346707-61-7
Molecular Formula:C₃₀H₄₀N₂O₈
Molecular Weight:556.656
Hs Code.:

Synonyms:(S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

Suppliers and Price of (S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

There total 8 articles about (S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 98254-05-8
(S)-2-(tert-butoxycarbonylamino)-4-hexynoic acid

: 346707-86-6
(S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-hydroxymethylbenzyl ester

: 346707-61-7
(S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

Guidance literature:: With dmap; 4-(dimethylamino)pyridine hydrochloride; dicyclohexyl-carbodiimide; In dichloromethane; for 16h; Heating;
DOI:10.1021/jo001734x

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 346707-61-7
(S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / aq. NaOH / dioxane / 3 h / 0 - 20 °C

2: 79 percent / N,N'-dicyclohexylcarbodiimide; DMAP / CH₂Cl₂ / 0 - 20 °C

3: 99 percent / N,N'-dicyclohexylcarbodiimide; DMAP; DMAP*HCl / CH₂Cl₂ / 16 h / Heating

With dmap; sodium hydroxide; 4-(dimethylamino)pyridine hydrochloride; dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jo001734x

Reference yield:

: 29834-76-2
(2S)-2-amino-4-hexynoic acid

: 346707-61-7
(S)-2-tert-butoxycarbonylamino-hex-4-ynoic acid 2-((S)-2-tert-butoxycarbonylamino-hex-4-ynoyloxy)benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / aq. NaOH / dioxane / 3 h / 0 - 20 °C

2: 79 percent / N,N'-dicyclohexylcarbodiimide; DMAP / CH₂Cl₂ / 0 - 20 °C

3: 99 percent / N,N'-dicyclohexylcarbodiimide; DMAP; DMAP*HCl / CH₂Cl₂ / 16 h / Heating

With dmap; sodium hydroxide; 4-(dimethylamino)pyridine hydrochloride; dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jo001734x