3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

Base Information

Chemical Name:3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A
CAS No.:105507-33-3
Molecular Formula:C₅₃H₆₆N₄O₂₀S₄
Molecular Weight:1207.39
Hs Code.:

Synonyms:3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

Suppliers and Price of 3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

There total 3 articles about 3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 107009-76-7
2',2''-di-O-acetyl-3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

: 105507-33-3
3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

Guidance literature:: Zemplen deacetylation;
DOI:10.1016/0008-6215(92)84101-W

Reference yield:

: 76550-53-3
6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

: 105507-33-3
3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / pyridine, 5percent NaHCO₃ / dimethylsulfoxide; H₂O / Ambient temperature

2: 88 mg / pyridine / 0.17 h / 0 - 5 °C

3: 88 percent / Zemplen deacetylation

With pyridine; sodium hydrogencarbonate; In water; dimethyl sulfoxide;
DOI:10.1016/0008-6215(92)84101-W

Reference yield:

: 106996-47-8
2',2''-di-O-acetyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosyl-kanamycin A

: 105507-33-3
3'-O-benzylsulfonyl-6'-N,4'-O-carbonyl-4'',6''-O-cyclohexylidene-1,3,3''-tri-N-tosylkanamycin A

Guidance literature:: Multi-step reaction with 2 steps

1: 88 mg / pyridine / 0.17 h / 0 - 5 °C

2: 88 percent / Zemplen deacetylation

With pyridine;
DOI:10.1016/0008-6215(92)84101-W