trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester

Base Information

• Chemical Name: trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester
• CAS No.: 791772-84-4
• Molecular Formula: C₂₅H₁₉F₆NO₆S₂
• Molecular Weight: 607.551
• Mol file: 791772-84-4.mol

Synonyms:trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester

Chemical Property of trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester

There total 4 articles about trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,6-dimethoxyphenyl)boronic acid (23112-96-1) → trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester (791772-84-4)

Guidance literature:

Multi-step reaction with 3 steps

1: Pd(PPh₃)4; K₂CO₃ / dimethylformamide

2: 48 percent / aq. HBr

3: K₂CO₃; Et₃N / CH₂Cl₂

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen bromide; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide; 1: Suzuki coupling reaction;

DOI:10.1021/jm0108505

Reference yield:

Trifluoro-methanesulfonic acid (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester (264599-06-6) → trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester (791772-84-4)

Guidance literature:

Multi-step reaction with 3 steps

1: Pd(PPh₃)4; K₂CO₃ / dimethylformamide

2: 48 percent / aq. HBr

3: K₂CO₃; Et₃N / CH₂Cl₂

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen bromide; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide; 1: Suzuki coupling reaction;

DOI:10.1021/jm0108505

Reference yield:

11-(2,6-dimethoxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline (713075-13-9) → trifluoro-methanesulfonic acid 2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-3-trifluoromethanesulfonyloxy-phenyl ester (791772-84-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 48 percent / aq. HBr

2: K₂CO₃; Et₃N / CH₂Cl₂

With hydrogen bromide; potassium carbonate; triethylamine; In dichloromethane;

DOI:10.1021/jm0108505

upstream raw materials:

N,N-phenylbistrifluoromethane-sulfonimide

2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzene-1,3-diol

(2,6-dimethoxyphenyl)boronic acid

Trifluoro-methanesulfonic acid (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester