tert-butyl 3-oxo-5-diazirinedodecanoate

Base Information

• Chemical Name: tert-butyl 3-oxo-5-diazirinedodecanoate
• CAS No.: 1608149-08-1
• Molecular Formula: C₁₆H₂₈N₂O₃
• Molecular Weight: 296.41
• Mol file: 1608149-08-1.mol

Synonyms:tert-butyl 3-oxo-5-diazirinedodecanoate

Chemical Property of tert-butyl 3-oxo-5-diazirinedodecanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of tert-butyl 3-oxo-5-diazirinedodecanoate

There total 2 articles about tert-butyl 3-oxo-5-diazirinedodecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

mono-tert-butyl malonate (40052-13-9) + 3-diazirinedecanoic acid (1608149-07-0) → tert-butyl 3-oxo-5-diazirinedodecanoate (1608149-08-1)

Guidance literature:

3-diazirinedecanoic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;

mono-tert-butyl malonate; With isopropylmagnesium chloride; In tetrahydrofuran; at 20 ℃; for 16h;

DOI:10.1002/ejoc.201300800

Reference yield:

mono-tert-butyl malonate (40052-13-9) → tert-butyl 3-oxo-5-diazirinedodecanoate (1608149-08-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / 1 h / 0 - 50 °C / Inert atmosphere

2.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

With isopropylmagnesium chloride; 1,1'-carbonyldiimidazole; In tetrahydrofuran;

DOI:10.1002/ejoc.201300800

upstream raw materials:

mono-tert-butyl malonate

3-diazirinedecanoic acid