(R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

Base Information

Chemical Name:(R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol
CAS No.:1617545-36-4
Molecular Formula:C₁₉H₁₈FN₃O₂
Molecular Weight:339.369
Hs Code.:

Synonyms:(R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

Suppliers and Price of (R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

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Chemical Property of (R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

Chemical Property:

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Technology Process of (R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

There total 3 articles about (R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1043869-98-2
(5-fluoro-2-methoxypyridin-4-yl)boronic acid

: 1613639-38-5
(R)-2-(5-bromo-pyridin-3-ylamino)-2-phenyl-ethanol

: 1617545-36-4
(R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; water; at 100 ℃; for 1h; Inert atmosphere; Microwave irradiation;

Reference yield:

: 56613-80-0
D-2-phenylglycinol

: 1617545-36-4
(R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; copper(l) iodide; L-proline / dimethyl sulfoxide / 100 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / 1,2-dimethoxyethane; water / 1 h / 100 °C / Inert atmosphere; Microwave irradiation

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; L-proline; In 1,2-dimethoxyethane; water; dimethyl sulfoxide;

Reference yield:

: 625-92-3
3,5-dibromopyridine

: 1617545-36-4
(R)-2-(5'-fluoro-2'-methoxy-[3,4']bipyridinyl-5-ylamino)-2-phenyl-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; copper(l) iodide; L-proline / dimethyl sulfoxide / 100 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / 1,2-dimethoxyethane; water / 1 h / 100 °C / Inert atmosphere; Microwave irradiation

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; L-proline; In 1,2-dimethoxyethane; water; dimethyl sulfoxide;