N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride

Base Information

Chemical Name:N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride
CAS No.:136539-31-6
Molecular Formula:C₂₃H₁₉N₅O₅S*ClH
Molecular Weight:513.961
Hs Code.:

Synonyms:N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride

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Chemical Property of N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride

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Technology Process of N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride

There total 2 articles about N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 131058-48-5
11-chloro-7-nitro-10H-indolo<3,2-b>quinoline

: 83209-83-0
4-methanesulfonamido-2-methoxyaniline hydrochloride

: 136539-31-6
N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride

Guidance literature:: In 2-ethoxy-ethanol; for 8h; Heating;
DOI:10.1248/cpb.39.1629

Reference yield:

: 80271-19-8
11-chloro-10H-indolo-[3,2-b]quinoline

: 136539-31-6
N-[3-Methoxy-4-(7-nitro-10H-indolo[3,2-b]quinolin-11-ylamino)-phenyl]-methanesulfonamide; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / HNO₃ / acetic acid / 12 h / Ambient temperature

2: 78 percent / 2-ethoxy-ethanol / 8 h / Heating

With nitric acid; In 2-ethoxy-ethanol; acetic acid;
DOI:10.1248/cpb.39.1629