(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

Base Information

Chemical Name:(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine
CAS No.:433922-90-8
Molecular Formula:C₂₂H₃₉NO₃SSi
Molecular Weight:425.708
Hs Code.:

Synonyms:(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

Suppliers and Price of (2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

There total 1 articles about (2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: N-[1-(tert-butyl-dimethyl-silanyloxymethyl)-2-hydroxy-4-methyl-pentyl]-2,4,6-trimethyl-benzenesulfonamide

: 433922-90-8
(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

Guidance literature:: With triphenylphosphine; In tetrahydrofuran;

Reference yield:

: 433922-90-8
(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

: [(2S,3R)-3-Isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridin-2-yl]-methanol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran;

Reference yield:

: 433922-90-8
(2S,3R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-isobutyl-1-(2,4,6-trimethyl-benzenesulfonyl)-aziridine

: 433922-96-4
3-{tert-butoxycarbonyl-[2-hydroxy-5-methyl-3-(2,4,6-trimethyl-benzenesulfonylamino)-hexyl]-amino}-N-isopropyl-succinamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Bu₄NF / tetrahydrofuran

2: NaH / tetrahydrofuran

3: 74 percent / DIPEA / propan-2-ol

4: 95 percent / Et₃N

With tetrabutyl ammonium fluoride; sodium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; isopropyl alcohol; 2: aza-Payne rearrangement;