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Reserpiline

Base Information Edit
  • Chemical Name:Reserpiline
  • CAS No.:131-02-2
  • Deprecated CAS:1356-83-8,37338-41-3,493020-80-7
  • Molecular Formula:C23H28 N2 O5
  • Molecular Weight:412.486
  • Hs Code.:
  • European Community (EC) Number:205-005-3
  • UNII:C0N6EP99UK
  • DSSTox Substance ID:DTXSID20927028
  • Nikkaji Number:J10.012I
  • Wikidata:Q27275019
  • Mol file:131-02-2.mol
Reserpiline

Synonyms:Reserpiline;Elliptamine;Reserpilin;131-02-2;(-)-Reserpiline;EINECS 205-005-3;UNII-C0N6EP99UK;C0N6EP99UK;Methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate;Methyl 16,17-didehydro-10,11-dimethoxy-19alpha-methyl-18-oxa-3beta,20alpha-yohimban-16-carboxylat;Reserpiline hydrochloride;methyl (4S,4aS,13bR,14aS)-10,11-dimethoxy-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate;Oxayohimban-16-carboxylic acid, 16,17-didehydro-10,11-dimethoxy-19-methyl-, methyl ester, (3-beta,19-alpha,20-alpha)-;RESERPILINE [MI];RESERPILINE [WHO-DD];SCHEMBL355882;DTXSID20927028;CHEBI:135667;Oxayohimban-16-carboxylic acid, 16,17-didehydro-10,11-dimethoxy-19-methyl-, methyl ester, (3.beta.,19.alpha.,20.alpha.)-;AKOS040753731;LS-99744;Q27275019;methyl 10,11-dimethoxy-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate;(3-beta,19-alpha,20-alpha)-16,17-Didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylic acid methyl ester;4H-INDOLO(2,3-A)PYRANO(3,4-G)QUINOLIZINE-1-CARBOXYLIC ACID, 4A,5,7,8,13,13B,14,14A-OCTAHYDRO-10,11-DIMETHOXY-4-METHYL-, METHYL ESTER, (4S,4AS,13BR,14AS)-;methyl (1R,15S,16S,20S)-6,7-dimethoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate

Suppliers and Price of Reserpiline
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Methyl(3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate
  • 2mg
  • $ 60.00
  • TRC
  • Methyl(3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate
  • 1mg
  • $ 45.00
Total 7 raw suppliers
Chemical Property of Reserpiline Edit
Chemical Property:
  • Vapor Pressure:5.34E-13mmHg at 25°C 
  • Boiling Point:569.9°Cat760mmHg 
  • PKA:17.95±0.60(Predicted) 
  • Flash Point:298.4°C 
  • PSA:73.02000 
  • Density:1.31g/cm3 
  • LogP:3.13390 
  • XLogP3:2.7
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:4
  • Exact Mass:412.19982200
  • Heavy Atom Count:30
  • Complexity:699
Purity/Quality:

98%min *data from raw suppliers

Methyl(3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC(=C(C=C45)OC)OC
  • Isomeric SMILES:C[C@H]1[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2C(=CO1)C(=O)OC)NC5=CC(=C(C=C45)OC)OC
  • Description An amorphous alkaloid present in Rauwolfia canescens and R. serpentina, the alkaloid forms several crystalline salts and derivatives including the hydrochloride, m.p. 205-7°C; [α]24D - 40° (c 0.44, EtOH); the tartrate, m.p. 190- 2°C; [α]20D - 50° (c 1.0, H20); the oxalate, m.p. 252°C; [α]20D - 4° (c 0.2, aqueous EtOH); the picrate, m.p. 173°C and the di-p-toluyl-L-tartrate, m.p. 194- 5° C (dec.).
Technology Process of Reserpiline

There total 8 articles about Reserpiline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium tetrahydroborate; mercury(II) diacetate; Yield given. Multistep reaction. Yields of byproduct given; 1.) acetic acid, H2O, 90 deg C, 1.5 h;
Guidance literature:
Multi-step reaction with 3 steps
1: 72 percent / NaHCO3 / dimethylformamide / 3 h / 60 °C
2: 72 percent / NaBH4, acetic acid / dioxane / 2 h / Heating
3: 1.) Hg(AcO)2, 2.) NaBH4 / 1.) acetic acid, H2O, 90 deg C, 1.5 h
With sodium tetrahydroborate; mercury(II) diacetate; sodium hydrogencarbonate; acetic acid; In 1,4-dioxane; N,N-dimethyl-formamide;
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