2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole

Base Information

• Chemical Name: 2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole
• CAS No.: 1394853-38-3
• Molecular Formula: C₄₃H₂₇F₆N₅O₆
• Molecular Weight: 823.708
• Mol file: 1394853-38-3.mol

Synonyms:2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole

Chemical Property of 2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole

There total 3 articles about 2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1, 2-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)ethane-1,2-dione (1394853-36-1) + 9-ethyl-9H-carbazole-2-carboxaldehyde (56166-62-2) → 2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole (1394853-38-3)

Guidance literature:

With ammonium acetate; acetic acid; for 14h; Inert atmosphere; Reflux;

DOI:10.1016/j.jfluchem.2012.06.011

Reference yield:

1,2-bis(4-methoxyphenyl)-1,2-ethanedione (1226-42-2) → 2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole (1394853-38-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen bromide; acetic acid / water / 24 h / Reflux

2: potassium carbonate / 6.5 h / 20 - 110 °C

3: ammonium acetate; acetic acid / 14 h / Inert atmosphere; Reflux

With ammonium acetate; hydrogen bromide; potassium carbonate; acetic acid; In water;

DOI:10.1016/j.jfluchem.2012.06.011

Reference yield:

4,4'-dihydroxybenzil (33288-79-8) → 2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole (1394853-38-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / 6.5 h / 20 - 110 °C

2: ammonium acetate; acetic acid / 14 h / Inert atmosphere; Reflux

With ammonium acetate; potassium carbonate; acetic acid;

DOI:10.1016/j.jfluchem.2012.06.011

upstream raw materials:

1, 2-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)ethane-1,2-dione

9-ethyl-9H-carbazole-2-carboxaldehyde

4,4'-dihydroxybenzil

1,2-bis(4-methoxyphenyl)-1,2-ethanedione

Downstream raw materials:

C₄₃H₃₁F₆N₅O₂