5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole

Base Information

• Chemical Name: 5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole
• CAS No.: 323203-53-8
• Molecular Formula: C₃₀H₃₆N₂O₂
• Molecular Weight: 456.628
• Mol file: 323203-53-8.mol

Synonyms:5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole

Chemical Property of 5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole

There total 2 articles about 5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenyllithium (591-51-5) + 5,5'-diformyl-3,3',4,4'-tetraethyl-2,2'-bipyrrole (152172-78-6) → 5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole (323203-53-8)

Guidance literature:

In tetrahydrofuran; diethyl ether; cyclohexane; at -50 - 20 ℃; for 4.5h;

DOI:10.1021/ja005588o

Reference yield:

3,4,3',4'-tetraethyl-1H,1H'-[2,2']-bipyrrole (152172-77-5) → 5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole (323203-53-8)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃

2: 95 percent / cyclohexane; diethyl ether; tetrahydrofuran / 4.5 h / -50 - 20 °C

With trichlorophosphate; In tetrahydrofuran; diethyl ether; cyclohexane;

DOI:10.1039/b518340e

Reference yield: 92.0%

5,5'-bis(phenylhydroxymethyl)-3,3',4,4'-tetraethyl-2,2'-bipyrrole (323203-53-8) → 6,6'-diphenyl-4,4',5,5'-tetraethyl-2,2'-diaza-3,3'-bifulvene

Guidance literature:

With dmap; di-tert-butyl dicarbonate; at 20 ℃; for 2h;

DOI:10.1039/b518340e

upstream raw materials:

phenyllithium

5,5'-diformyl-3,3',4,4'-tetraethyl-2,2'-bipyrrole

3,4,3',4'-tetraethyl-1H,1H'-[2,2']-bipyrrole