N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid

Base Information

• Chemical Name: N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid
• CAS No.: 77919-01-8
• Molecular Formula: C₁₇H₂₅N₃O₃
• Molecular Weight: 319.404
• Mol file: 77919-01-8.mol

Synonyms:N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid

Chemical Property of N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid

There total 1 articles about N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.4%

2-Aethyl-2-phenylmalonsaeuremonoamid (24130-91-4,52165-62-5,52165-64-7) + 3-dimethylamino-2,2-dimethyl-2H-azirine (54856-83-6) → N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid (77919-01-8)

Guidance literature:

In acetonitrile; for 12h; Ambient temperature;

DOI:10.1002/hlca.19850680220

Reference yield: 80.1%

thiophenol (108-98-5) + N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid (77919-01-8) → N-(1-Phenylthiocarbonyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid (77919-13-2)

Guidance literature:

With hydrogenchloride; In acetonitrile;

DOI:10.1002/hlca.19850680220

Reference yield:

N-(1-Dimethylcarbamoyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid (77919-01-8) → 6-Aethyl-3,3-dimethyl-6-phenylperhydro-1,4-diazepin-2,5,7-trion

Guidance literature:

Multi-step reaction with 2 steps

1: 80.1 percent / HCl(g) / acetonitrile

2: 75.1 percent / NaH / toluene

With hydrogenchloride; sodium hydride; In toluene; acetonitrile;

DOI:10.1002/hlca.19850680220

upstream raw materials:

2-Aethyl-2-phenylmalonsaeuremonoamid

3-dimethylamino-2,2-dimethyl-2H-azirine

Downstream raw materials:

N-(1-Phenylthiocarbonyl-1-methylaethyl)-2-aethyl-2-phenylmalonamid