ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate

Base Information

Chemical Name:ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate
CAS No.:470477-65-7
Molecular Formula:C₃₀H₃₆ClN₃O₅S
Molecular Weight:586.152
Hs Code.:

Synonyms:ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate

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Chemical Property of ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate

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Technology Process of ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate

There total 1 articles about ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 470477-64-6
ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]sulfamoylacetate

: 98116-50-8
3-(3-cyanophenyl)-2-(E)-propen-1-ol

: 470477-65-7
ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 0 - 20 ℃;

Reference yield: 80.0%

: 470477-65-7
ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate

: ethyl N-[3-(3-amidinophenyl)-2-(E)-propenyl]-N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]sulfamoylacetate dihydrochloride

Guidance literature:: ethyl N-[3-chloro-4-(1-cyclopentylpiperidin-4-yloxy)phenyl]-N-[3-(3-cyanophenyl)-2-(E)-propenyl]sulfamoylacetate; With hydrogenchloride; ethanol; In dichloromethane; at 0 - 20 ℃; for 6h;

With ammonia; ammonium chloride; In ethanol; water; at 20 ℃;

With hydrogenchloride; In 1,4-dioxane; ethanol; water;