Technology Process of (R,E)-4-methylnon-7-en-2-ynyl 4-methylbenzenesulfonate
There total 5 articles about (R,E)-4-methylnon-7-en-2-ynyl 4-methylbenzenesulfonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1016/j.tet.2013.05.095
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: triethylamine; triphenyl phosphite; bromine / dichloromethane / 1.5 h / -78 - 20 °C / Inert atmosphere
2.1: ozone / dichloromethane / 0.33 h / -78 °C
2.2: 1 h / -78 - 20 °C
3.1: potassium hexamethylsilazane / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
4.1: potassium tert-butylate; 18-crown-6 ether / Petroleum ether / 12 h / 80 °C / Inert atmosphere
5.1: triethylamine; dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
With
triphenyl phosphite; dmap; 18-crown-6 ether; potassium tert-butylate; bromine; potassium hexamethylsilazane; ozone; triethylamine;
In
tetrahydrofuran; dichloromethane; Petroleum ether;
3.1: |Julia-Kocienski Olefination;
DOI:10.1016/j.tet.2013.05.095
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: ozone / dichloromethane / 0.33 h / -78 °C
1.2: 1 h / -78 - 20 °C
2.1: potassium hexamethylsilazane / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
3.1: potassium tert-butylate; 18-crown-6 ether / Petroleum ether / 12 h / 80 °C / Inert atmosphere
4.1: triethylamine; dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
With
dmap; 18-crown-6 ether; potassium tert-butylate; potassium hexamethylsilazane; ozone; triethylamine;
In
tetrahydrofuran; dichloromethane; Petroleum ether;
2.1: |Julia-Kocienski Olefination;
DOI:10.1016/j.tet.2013.05.095
