9-trityloxynonanal

Base Information

• Chemical Name: 9-trityloxynonanal
• CAS No.: 157730-79-5
• Molecular Formula: C₂₈H₃₂O₂
• Molecular Weight: 400.561
• Mol file: 157730-79-5.mol

Synonyms:9-trityloxynonanal

Chemical Property of 9-trityloxynonanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-trityloxynonanal

There total 4 articles about 9-trityloxynonanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

9-hydroxynonyl-1-triphenylmethylether (82777-72-8) → 9-trityloxynonanal (157730-79-5)

Guidance literature:

With Dess-Martin periodane; In dichloromethane;

DOI:10.1016/0957-4166(94)80156-8

Reference yield:

trityl chloride (76-83-5) → 9-trityloxynonanal (157730-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 16.5 h / 0 - 20 °C

2: DMSO; (COCl)2; Et₃N / CH₂Cl₂ / 1.33 h / -70 - 10 °C

With pyridine; oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane;

DOI:10.1021/jm0310232

Reference yield:

trityl chloride (76-83-5) → 9-trityloxynonanal (157730-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 43 percent / dimethylaminopyridine, Et₃N / dimethylformamide / 12 h / 25 °C

2: 99 percent / Dess-Martin periodinane / CH₂Cl₂ / 6 h / 25 °C

With dmap; Dess-Martin periodane; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/S0957-4166(97)00186-9

upstream raw materials:

9-hydroxynonyl-1-triphenylmethylether

trityl chloride

Downstream raw materials:

(R)-(+)-9-trityloxy-2-decanol

1-trityloxy-(R)-decan-9-ol

9-trityloxynonanoic acid

Refernces

• 1、 Jones, Graham B.,Huber, Robert S.,Chapman, Brant J.. "Catalytic enantioselective synthesis of macrolides via asymmetric alkylation". . p. 1797 - 1809. Retrieved 2007/10/03.