4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide

Base Information

• Chemical Name: 4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide
• CAS No.: 169266-39-1
• Molecular Formula: C₂₂H₃₃N₅O₂
• Molecular Weight: 399.536
• Mol file: 169266-39-1.mol

Synonyms:4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide

Chemical Property of 4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide

Chemical Property:

Purity/Quality:

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Technology Process of 4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide

There total 1 articles about 4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-(3-nitro-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide → 4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide (169266-39-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 40h; under 750.06 Torr;

DOI:10.1002/ardp.19953280411

Reference yield: 86.0%

Benzoyl isothiocyanate (532-55-8) + 4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide (169266-39-1) → N-benzoyl-N'-<1-<3-propyl>carbamoyl>propyl>-3-pyrazolyl>thiourea

Guidance literature:

In chloroform; for 1h; Ambient temperature;

DOI:10.1002/ardp.19953280411

Reference yield: 74.0%

N-<(phenoxy)(2,2,2-trifluoroethylamino)methylene>benzamide (169266-33-5) + 4-(3-amino-1-pyrazolyl)-N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>butanamide (169266-39-1) → N-propyl>carbamoyl>propyl>-3-pyrazolyl>-N'-(2,2,2-trifluoroethyl)diaminomethylene>benzamide

Guidance literature:

In pyridine; for 5h; Heating;

DOI:10.1002/ardp.19953280411