Technology Process of 3-phenyl-6-phthalimidyl-1,2-hexadiene
There total 6 articles about 3-phenyl-6-phthalimidyl-1,2-hexadiene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
di-isopropyl azodicarboxylate; N-ethyl-N,N-diisopropylamine; triphenylphosphine;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/ol201395p
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 0 °C / Inert atmosphere
1.2: 12 h / -78 - 20 °C / Inert atmosphere
2.1: potassium carbonate / diethyl ether / 0.5 h / -10 °C
3.1: copper(I) bromide / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
5.1: di-isopropyl azodicarboxylate; N-ethyl-N,N-diisopropylamine; triphenylphosphine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
With
n-butyllithium; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; copper(I) bromide;
In
tetrahydrofuran; diethyl ether; hexane;
DOI:10.1021/ol201395p
- Guidance literature:
-
Multi-step reaction with 3 steps
1: copper(I) bromide / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
3: di-isopropyl azodicarboxylate; N-ethyl-N,N-diisopropylamine; triphenylphosphine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
With
di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; N-ethyl-N,N-diisopropylamine; triphenylphosphine; copper(I) bromide;
In
tetrahydrofuran;
DOI:10.1021/ol201395p
