3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione

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Chemical Name:3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione
CAS No.:1262304-40-4
Molecular Formula:C₃₂H₂₅N₇O₄
Molecular Weight:571.595
Hs Code.:

Synonyms:3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione

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Chemical Property of 3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione

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Technology Process of 3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione

There total 4 articles about 3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1516-60-5
4-nitrophenyl azide

: 1262304-13-1
C₂₆H₂₁N₃O₂

: 1262304-40-4
3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; acetonitrile; tert-butyl alcohol; at 100 ℃; for 0.333333h; Microwave irradiation; Combinatorial reaction / High throughput screening (HTS);
DOI:10.1039/c0cc01166e

Reference yield:

: 942434-83-5
C₁₅H₁₆N₂O

: 1262304-40-4
3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 4 h / 0 - 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; acetonitrile; tert-butyl alcohol / 0.33 h / 100 °C / Microwave irradiation; Combinatorial reaction / High throughput screening (HTS)

With copper(ll) sulfate pentahydrate; potassium tert-butylate; sodium L-ascorbate; In tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;
DOI:10.1039/c0cc01166e

Reference yield:

: 151490-40-3
methyl 2-(1-methyl-1H-indol-3-yl)-2-oxoacetate

: 1262304-40-4
3-(1-methyl-1H-indol-3-yl)-4-(1-(3-(1-(4-nitro-phenyl)-1H-(1,2,3)triazol-4-yl)-propyl)-1H-indol-3-yl)-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 4 h / 0 - 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; acetonitrile; tert-butyl alcohol / 0.33 h / 100 °C / Microwave irradiation; Combinatorial reaction / High throughput screening (HTS)

With copper(ll) sulfate pentahydrate; potassium tert-butylate; sodium L-ascorbate; In tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;
DOI:10.1039/c0cc01166e