1- piperazine

Base Information

• Chemical Name: 1- piperazine
• CAS No.: 84359-49-9
• Molecular Formula: C₁₉H₂₄N₂O₂
• Molecular Weight: 312.412

Synonyms:1- piperazine

Chemical Property of 1- piperazine

Chemical Property:

Purity/Quality:

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Technology Process of 1- piperazine

There total 11 articles about 1- piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 1- piperazine (84359-49-9)

Guidance literature:

Reference yield: 71.0%

ethyl <4-(bis (4-methoxyphenyl) methyl)-1-piperazinyl> carboxylate (154544-62-4) → 1- piperazine (84359-49-9)

Guidance literature:

With sodium hydroxide; In methanol; for 72h; Heating;

DOI:10.1016/0223-5234(93)90049-K

Reference yield: 60.0%

piperazine (110-85-0) + (bis(4-methoxyphenyl)methyl)triphenylphosphonium trifluoromethanesulfonate → 1- piperazine (84359-49-9)

Guidance literature:

In dimethyl sulfoxide; Inert atmosphere; Sealed tube; Heating;

DOI:10.1002/anie.202111164

upstream raw materials:

ethyl <4-(bis (4-methoxyphenyl) methyl)-1-piperazinyl> carboxylate

piperazine

4,4'-dimethoxydiphenylmethyl chloride

4,4'-Dimethoxybenzhydrol

Downstream raw materials:

C₃₄H₃₆N₂O₃

C₂₄H₂₆N₄O₆

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