Chemical Property of Ipamorelin
Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Refractive Index:1.624
- Boiling Point:1185.464 °C at 760 mmHg
- PKA:13.04±0.46(Predicted)
- Flash Point:670.744 °C
- PSA：240.21000
- Density:1.264 g/cm3
- LogP:4.54610
- Storage Temp.:-20°C Freezer
- Solubility.:Acetonitrile (Slightly, Heated), Methanol (Very Slightly), Water (Slightly)
- XLogP3:1.8
- Hydrogen Bond Donor Count:8
- Hydrogen Bond Acceptor Count:8
- Rotatable Bond Count:19
- Exact Mass:711.38566570
- Heavy Atom Count:52
- Complexity:1200
- Purity/Quality:
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99% ,99.9%, *data from raw suppliers
Ipamorelin Acetate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC(C)(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC3=CC=CC=C3C=C2)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCCN)C(=O)N)N
- Isomeric SMILES:CC(C)(C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC3=CC=CC=C3C=C2)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N)N
- Recent ClinicalTrials:Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus
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Description
Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.
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Uses
Ipamorelin was originally developed by Novo Nordisk, and was investigated in phase II clinical trials by Helsinn Therapeutics for the treatment of postoperative ileus, but was discontinued due to lack of efficacy.Ipamorelin has been used by athletes as a performance enhancing drug. Ipamorelin is a metabolite of growth hormone releasing peptides (GHRPs). Ipamorelin is a pentapeptide with strong growth hormone releasing potency that evokes insulin release from pancrease of normal and diabetic rats.
