C₂₆H₃₅BrO₃

Base Information

• Chemical Name: C₂₆H₃₅BrO₃
• CAS No.: 1213270-10-0
• Molecular Formula: C₂₆H₃₅BrO₃
• Molecular Weight: 475.466
• Mol file: 1213270-10-0.mol

Synonyms:C₂₆H₃₅BrO₃

Chemical Property of C₂₆H₃₅BrO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₃₅BrO₃

There total 6 articles about C₂₆H₃₅BrO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C23H30Br2O3 (1213270-09-7) + 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (72824-04-5) → C26H35BrO3 (1213270-10-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydroxide; In water; toluene; at 90 ℃; for 0.833333h; Inert atmosphere;

DOI:10.1021/ol100214X

Reference yield:

C23H31BrO3 (1213270-15-5) → C26H35BrO3 (1213270-10-0)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine; sodium acetate / acetic acid / 4 h / 60 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydroxide / water; toluene / 0.83 h / 90 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; bromine; sodium acetate; sodium hydroxide; In water; acetic acid; toluene; 2: Suzuki reaction;

DOI:10.1016/j.bmcl.2011.06.054

Reference yield:

4-bromo-phenol (106-41-2) → C26H35BrO3 (1213270-10-0)

Guidance literature:

Multi-step reaction with 4 steps

1: diphenyl hydrogen phosphate / dichloromethane / 4.5 h / 0 °C / Inert atmosphere

2: dmap; triethylamine / dichloromethane / 1.17 h / 0 °C / Inert atmosphere

3: bromine; sodium acetate / acetic acid / 4 h / 60 °C / Inert atmosphere

4: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydroxide / water; toluene / 0.83 h / 90 °C / Inert atmosphere

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; diphenyl hydrogen phosphate; bromine; sodium acetate; triethylamine; sodium hydroxide; In dichloromethane; water; acetic acid; toluene; 4: Suzuki reaction;

DOI:10.1016/j.bmcl.2011.06.054

upstream raw materials:

C₂₃H₃₀Br₂O₃

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

C₂₁H₂₉BrO₂

C₂₃H₃₁BrO₃

Downstream raw materials:

C₄₀H₅₃NO₅

clovanemagnolol

Refernces

• 1、 Khaing, Zin,Kang, Danby,Camelio, Andrew M.,Schmidt, Christine E.,Siegel, Dionicio. "Hippocampal and cortical neuronal growth mediated by the small molecule natural product clovanemagnolol". supporting information; experimental part. p. 4808 - 4812. Retrieved 2011/09/21.