deoxylimonol

Base Information

• Chemical Name: deoxylimonol
• CAS No.: 83991-64-4
• Molecular Formula: C₂₆H₃₂O₇
• Molecular Weight: 456.536
• Mol file: 83991-64-4.mol

Synonyms:4H,6H,8H-Pyrano[4',3':3,3a]isobenzofuro[5,4-f][2]benzopyran-4,11(7H)-dione,9-(3-furanyl)-1,2a,3,6b,8a,9,12b,13,14,14a-decahydro-13-hydroxy-1,1,8a,12b-tetramethyl-,(2aS,6aR,6bS,8aR,9R,12bR,13R,14aR)- (9CI); Limonoic acid,14,15-deepoxy-14,15-didehydro-7-deoxo-7-hydroxy-, 3,19:16,17-dilactone, (7a)-;4H,6H,8H-Pyrano[4',3':3,3a]isobenzofuro[5,4-f][2]benzopyran-4,11(7H)-dione,9-(3-furanyl)-1,2a,3,6b,8a,9,12b,13,14,14a-decahydro-13-hydroxy-1,1,8a,12b-tetramethyl-,[2aS-(2aa,6aS*,6ba,8aa,9a,12bb,13a,14aa)]-; Deoxy-a-limonol

Chemical Property of deoxylimonol

Chemical Property:

• PSA: 95.20000
• LogP: 3.71800

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of deoxylimonol

There total 4 articles about deoxylimonol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

desoxylimonin (989-23-1) → Desoxyepilimonol (120523-05-9,83991-64-4)

Guidance literature:

With methanol; sodium tetrahydroborate; In dichloromethane; at -78 ℃; for 0.25h;

DOI:10.1002/anie.202104228

Reference yield:

Limonin (1180-71-8,42867-83-4) → Desoxyepilimonol (120523-05-9,83991-64-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen iodide; acetic acid / 12 h / Reflux

2: sodium tetrahydroborate; methanol / dichloromethane / 0.25 h / -78 °C

With methanol; sodium tetrahydroborate; hydrogen iodide; acetic acid; In dichloromethane;

DOI:10.1002/anie.202104228

Reference yield:

limonol → deoxylimonol (83991-64-4)

Guidance literature:

With chromium dichloride; acetic acid; In acetonitrile; at 25 ℃; for 72h; Yield given;

DOI:10.1016/0031-9422(82)85203-5

upstream raw materials:

Limonin

desoxylimonin

Refernces

• 1、 Furiassi, Lucia,Hergenrother, Paul J.,Tonogai, Emily J.. "Limonin as a Starting Point for the Construction of Compounds with High Scaffold Diversity". . p. 16119 - 16128. Retrieved 2021/06/14.