Butanoic acid, 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)-, ethyl ester

Base Information

Chemical Name:Butanoic acid, 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)-, ethyl ester
CAS No.:87540-59-8
Molecular Formula:C₂₂H₂₂N₄O₄
Molecular Weight:406.441
Hs Code.:
DSSTox Substance ID:DTXSID50236433
Wikidata:Q83118395

Synonyms:Butanoic acid, 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)-, ethyl ester;Ethyl 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)butanoate;87540-59-8;SCHEMBL10663935;DTXSID50236433;LS-46344

Suppliers and Price of Butanoic acid, 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Butanoic acid, 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)-, ethyl ester

Chemical Property:

Density:1.3g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:406.16410520
Heavy Atom Count:30
Complexity:557

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CCCOC1=NN2C(=NN=C2C3=CC=CC=C31)C4=CC=C(C=C4)OC

Technology Process of Butanoic acid, 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)-, ethyl ester

There total 5 articles about Butanoic acid, 4-((3-(4-methoxyphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-yl)oxy)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 3153-36-4
4-chloro-butyric acid ethyl ester

: 87540-94-1
6-hydroxy-3-(4-methoxyphenyl)-1,2,4-triazolo[3,4-a]phthalazine

: 87540-59-8
ethyl 4-<<3-(4'-methoxyphenyl)-1,2,4-triazolo<3,4-a>phthalazine-6-yl>-oxy>butanoate

Guidance literature:: In dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield: 59.0%

: 87540-59-8
ethyl 4-<<3-(4'-methoxyphenyl)-1,2,4-triazolo<3,4-a>phthalazine-6-yl>-oxy>butanoate

Guidance literature:

Reference yield:

: 51935-42-3,59275-72-8
1-chloro-4-hydrazinophthalazine

: 87540-59-8
ethyl 4-<<3-(4'-methoxyphenyl)-1,2,4-triazolo<3,4-a>phthalazine-6-yl>-oxy>butanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent

2: 71 percent / Na / 1.) 8 h, 120 deg C; 2.) EtOH, 15 min

3: 1.) NaH / 1.) DMF, oil, 1 h; 2.) 60 deg C, 14 h

With sodium; sodium hydride;