1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(4-methylphenyl)-

Base Information

Chemical Name:1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(4-methylphenyl)-
CAS No.:87540-39-4
Molecular Formula:C22H25N5O2
Molecular Weight:391.4662
Hs Code.:
DSSTox Substance ID:DTXSID30236416
Wikidata:Q83118371
ChEMBL ID:CHEMBL13869

Synonyms:BRN 6443636;1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(4-methylphenyl)-;N,N-Bis(2-methoxyethyl)-3-(4-methylphenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-amine;87540-39-4;CHEMBL13869;DTXSID30236416;LS-156553

Suppliers and Price of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(4-methylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(4-methylphenyl)-

Chemical Property:

Density:1.22g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:391.20082506
Heavy Atom Count:29
Complexity:494

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NN=C3N2N=C(C4=CC=CC=C43)N(CCOC)CCOC

Technology Process of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(4-methylphenyl)-

There total 4 articles about 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 111-95-5
Bis-(2-methoxyethyl)amine

: 113628-61-8
6-Chloro-3-p-tolyl-[1,2,4]triazolo[3,4-a]phthalazine

: 87540-39-4
Bis-(2-methoxy-ethyl)-(3-p-tolyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-amine

Guidance literature:: at 140 ℃; for 30h;
DOI:10.1021/jm00401a010

Reference yield:

: 51935-42-3,59275-72-8
1-chloro-4-hydrazinophthalazine

: 87540-39-4
Bis-(2-methoxy-ethyl)-(3-p-tolyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / 0.1N HCl / 0.17 h / 60 °C

2: 81 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 80 percent / 30 h / 140 °C

With hydrogenchloride; bromine; sodium acetate; In acetic acid;
DOI:10.1021/jm00401a010

Reference yield:

: 104-87-0
4-methyl-benzaldehyde

: 87540-39-4
Bis-(2-methoxy-ethyl)-(3-p-tolyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / 0.1N HCl / 0.17 h / 60 °C

2: 81 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 80 percent / 30 h / 140 °C

With hydrogenchloride; bromine; sodium acetate; In acetic acid;
DOI:10.1021/jm00401a010