[(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

Base Information

Chemical Name:[(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid
CAS No.:1401937-82-3
Molecular Formula:C₂₆H₃₂BNO₄
Molecular Weight:433.355
Hs Code.:

Synonyms:[(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

Suppliers and Price of [(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

There total 7 articles about [(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1401938-24-6
[(16E,17β)-16-(3-carbamoylbenzylidene)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

: 1401937-82-3
[(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 24h; Inert atmosphere;

Reference yield:

: (3aS,3bR,9bS,11aS)‐11a‐methyl‐7‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)‐1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH‐cyclopenta[a]phenanthren‐1‐one

: 1401937-82-3
[(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / ethanol; water / 0.5 h / Reflux

2: sodium tetrahydroborate; methanol / 1 h / 20 °C

3: hydrogen / palladium 10% on activated carbon / ethanol / 24 h / 20 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; hydrogen; potassium hydroxide; palladium 10% on activated carbon; In ethanol; water;

Reference yield:

: 92817-04-4
estrone triflate

: 1401937-82-3
[(16β,17β)-16-(3-carbamoylbenzyl)-17-hydroxyestra-1(10),2,4-trien-3-yl]boronic acid

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II) / 1,4-dioxane / 24 h / 100 °C / Inert atmosphere

2: potassium hydroxide / ethanol; water / 0.5 h / Reflux

3: sodium tetrahydroborate; methanol / 1 h / 20 °C

4: hydrogen / palladium 10% on activated carbon / ethanol / 24 h / 20 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; hydrogen; triethylamine; potassium hydroxide; [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); palladium 10% on activated carbon; In 1,4-dioxane; ethanol; water;