Technology Process of (-)-indolactam-Phg
There total 7 articles about (-)-indolactam-Phg which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
dimethyl sulfoxide;
for 12h;
Streptoverticillium blastmyceticum NA34-17, in a medium consisting of 1percent glucose, 1percent polypeptone, 1 percent meat extract, 0.5 percent NaCl; pH 6.6;
DOI:10.1016/S0040-4020(01)80978-9
- Guidance literature:
-
Multi-step reaction with 4 steps
1: NaH / tetrahydrofuran / 24 h / Ambient temperature
2: N-hydroxysuccinimide, 1,3-dicyclohexylcarbodiimide / tetrahydrofuran / 1) - 20 deg C, 1 h, 2) r.t., 24 h
3: 2M HCl / dioxane / 0.83 h
4: 1.2 percent / dimethylsulfoxide / 12 h / Streptoverticillium blastmyceticum NA34-17, in a medium consisting of 1percent glucose, 1percent polypeptone, 1 percent meat extract, 0.5 percent NaCl; pH 6.6
With
hydrogenchloride; 1-hydroxy-pyrrolidine-2,5-dione; sodium hydride; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; 1,4-dioxane; dimethyl sulfoxide;
DOI:10.1016/S0040-4020(01)80978-9
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine / dioxane; H2O / 4 h / Ambient temperature
2: NaH / tetrahydrofuran / 24 h / Ambient temperature
3: N-hydroxysuccinimide, 1,3-dicyclohexylcarbodiimide / tetrahydrofuran / 1) - 20 deg C, 1 h, 2) r.t., 24 h
4: 2M HCl / dioxane / 0.83 h
5: 1.2 percent / dimethylsulfoxide / 12 h / Streptoverticillium blastmyceticum NA34-17, in a medium consisting of 1percent glucose, 1percent polypeptone, 1 percent meat extract, 0.5 percent NaCl; pH 6.6
With
hydrogenchloride; 1-hydroxy-pyrrolidine-2,5-dione; sodium hydride; triethylamine; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; 1,4-dioxane; water; dimethyl sulfoxide;
DOI:10.1016/S0040-4020(01)80978-9
