Technology Process of C30H47NO6
There total 15 articles about C30H47NO6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,6-di-tert-butyl-4-methyl-phenol;
In
benzene;
for 4h;
stereoselective reaction;
Inert atmosphere;
Reflux;
DOI:10.1016/j.tetlet.2010.11.012
- Guidance literature:
-
Multi-step reaction with 13 steps
2: tetrabutyl ammonium fluoride
3: pyridine
4: potassium tert-butylate
5: lithium aluminium tetrahydride / diethyl ether / -20 °C
6: sodium hydrogencarbonate; Dess-Martin periodane
7: tetrahydrofuran / -78 °C
8: dmap / dichloromethane
9: diisobutylaluminium hydride / -78 °C
10: sodium hydrogencarbonate; Dess-Martin periodane
11: potassium fluoride / isopropyl alcohol / 24 h / 22 °C
12: methanesulfonyl chloride; triethylamine / dichloromethane / 0.17 h / 0 °C
13: 2,6-di-tert-butyl-4-methyl-phenol / benzene / 4 h / Inert atmosphere; Reflux
With
pyridine; dmap; potassium fluoride; lithium aluminium tetrahydride; 2,6-di-tert-butyl-4-methyl-phenol; potassium tert-butylate; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; sodium hydrogencarbonate; Dess-Martin periodane; methanesulfonyl chloride; triethylamine;
In
tetrahydrofuran; diethyl ether; dichloromethane; isopropyl alcohol; benzene;
6: Dess-Martin oxidation / 7: Aldol condensation / 10: Dess-Martin oxidation / 11: Henry reaction / 13: Intramolecular Diels-Alder reaction;
DOI:10.1016/j.tetlet.2010.11.012
- Guidance literature:
-
Multi-step reaction with 12 steps
1: tetrabutyl ammonium fluoride
2: pyridine
3: potassium tert-butylate
4: lithium aluminium tetrahydride / diethyl ether / -20 °C
5: sodium hydrogencarbonate; Dess-Martin periodane
6: tetrahydrofuran / -78 °C
7: dmap / dichloromethane
8: diisobutylaluminium hydride / -78 °C
9: sodium hydrogencarbonate; Dess-Martin periodane
10: potassium fluoride / isopropyl alcohol / 24 h / 22 °C
11: methanesulfonyl chloride; triethylamine / dichloromethane / 0.17 h / 0 °C
12: 2,6-di-tert-butyl-4-methyl-phenol / benzene / 4 h / Inert atmosphere; Reflux
With
pyridine; dmap; potassium fluoride; lithium aluminium tetrahydride; 2,6-di-tert-butyl-4-methyl-phenol; potassium tert-butylate; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; sodium hydrogencarbonate; Dess-Martin periodane; methanesulfonyl chloride; triethylamine;
In
tetrahydrofuran; diethyl ether; dichloromethane; isopropyl alcohol; benzene;
5: Dess-Martin oxidation / 6: Aldol condensation / 9: Dess-Martin oxidation / 10: Henry reaction / 12: Intramolecular Diels-Alder reaction;
DOI:10.1016/j.tetlet.2010.11.012
