1-Methyl-4-((2,4,5-trichlorophenoxy)acetyl)piperazine hydrochloride

Base Information

Chemical Name:1-Methyl-4-((2,4,5-trichlorophenoxy)acetyl)piperazine hydrochloride
CAS No.:86746-03-4
Molecular Formula:C₁₃H₁₅Cl₃N₂O₂*ClH
Molecular Weight:374.094
Hs Code.:
DSSTox Substance ID:DTXSID00235794
Mol file:86746-03-4.mol

Synonyms:1-Methyl-4-((2,4,5-trichlorophenoxy)acetyl)piperazine hydrochloride;86746-03-4;Piperazine, 1-methyl-4-((2,4,5-trichlorophenoxy)acetyl)-, monohydrochloride;C13H15Cl3N2O2.ClH;DTXSID00235794;C13-H15-Cl3-N2-O2.Cl-H;LS-113013

Suppliers and Price of 1-Methyl-4-((2,4,5-trichlorophenoxy)acetyl)piperazine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-METHYL-4-((2,4,5-TRICHLOROPHENOXY)ACETYL)PIPERAZINE HYDROCHLORIDE 95.00%
5MG
$ 497.11

Total 3 raw suppliers

Chemical Property of 1-Methyl-4-((2,4,5-trichlorophenoxy)acetyl)piperazine hydrochloride

Chemical Property:

Vapor Pressure:3.97E-09mmHg at 25°C
Boiling Point:473.3°C at 760 mmHg
Flash Point:240.1°C
PSA：32.78000
LogP:3.47740
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:373.993638
Heavy Atom Count:21
Complexity:338

Purity/Quality:: 1-METHYL-4-((2,4,5-TRICHLOROPHENOXY)ACETYL)PIPERAZINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C(=O)COC2=CC(=C(C=C2Cl)Cl)Cl.Cl

Technology Process of 1-Methyl-4-((2,4,5-trichlorophenoxy)acetyl)piperazine hydrochloride

There total 3 articles about 1-Methyl-4-((2,4,5-trichlorophenoxy)acetyl)piperazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 109-01-3
1-methyl-piperazine

: 1928-37-6
methyl 2,4,5-trichlorophenoxyacetate

: 86746-03-4
1-(4-Methyl-piperazin-1-yl)-2-(2,4,5-trichloro-phenoxy)-ethanone; hydrochloride

Guidance literature:: With hydrogenchloride; 1.) ethanol, reflux 20 h, 2.) ether;
DOI:10.1135/cccc19831089

Reference yield:

: 93-76-5
2,4,5-Trichlorophenoxyacetic acid

: 86746-03-4
1-(4-Methyl-piperazin-1-yl)-2-(2,4,5-trichloro-phenoxy)-ethanone; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / acetone; H₂O / 8 h / Heating

2: 72 percent / HCl / 1.) ethanol, reflux 20 h, 2.) ether

With hydrogenchloride; potassium carbonate; In water; acetone;
DOI:10.1135/cccc19831089

Reference yield:

: 95-95-4
2,4,5-trichlorophenol

: 86746-03-4
1-(4-Methyl-piperazin-1-yl)-2-(2,4,5-trichloro-phenoxy)-ethanone; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / NaOH / H₂O / 1.) 95 deg C, 45 min, 2.) 2.5 h.

2: K₂CO₃ / acetone; H₂O / 8 h / Heating

3: 72 percent / HCl / 1.) ethanol, reflux 20 h, 2.) ether

With hydrogenchloride; sodium hydroxide; potassium carbonate; In water; acetone;
DOI:10.1135/cccc19831089