[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester

Base Information

Chemical Name:[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester
CAS No.:957796-54-2
Molecular Formula:C₂₁H₂₂F₂N₂O₄
Molecular Weight:404.413
Hs Code.:

Synonyms:[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester

Suppliers and Price of [4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of [4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of [4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester

There total 1 articles about [4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1292836-43-1
C₁₃H₁₆F₂N₂O₂

: 501-53-1,94274-21-2
benzyl chloroformate

: 957796-54-2
[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester

Guidance literature:: With sodium hydrogencarbonate; In toluene; for 1.16667h;

Reference yield: 53.0%

: 957796-54-2
[4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester

: 60456-26-0
(R)-glycidyl butyrate

: (R)-N-{3-[4-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluorophenyl]-2-oxo-oxazolidin-5-yl}methyl alcohol

Guidance literature:: [4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester; With n-butyllithium; In tetrahydrofuran; hexane; at 40 ℃; for 1.16667h; Inert atmosphere;

(R)-glycidyl butyrate; In tetrahydrofuran; hexane; for 1.25h;