Technology Process of ARM-H
There total 7 articles about ARM-H which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(ll) sulfate pentahydrate; sodium L-ascorbate;
In
water; tert-butyl alcohol;
at 125 ℃;
for 0.333333h;
Microwave irradiation;
DOI:10.1021/ja9057647
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / N,N-dimethyl-formamide; toluene / 3 h / 20 °C
2: triphenylphosphine; water / tetrahydrofuran
3: triethylamine / ethanol / 2 h / Reflux
4: sodium L-ascorbate; copper(ll) sulfate pentahydrate / water; tert-butyl alcohol / 0.33 h / 125 °C / Capped vessel; Microwave irradiation
With
water; sodium hydride; triethylamine; triphenylphosphine;
copper(ll) sulfate pentahydrate; sodium L-ascorbate;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; toluene; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / 1,2-dimethoxyethane / 2 h
1.2: 2 h / 45 °C
2.1: phosphorus trichloride / ethyl acetate / 2 h
2.2: 0 °C / pH 2
3.1: sodium L-ascorbate; copper(ll) sulfate pentahydrate / water; tert-butyl alcohol / 0.33 h / 125 °C / Capped vessel; Microwave irradiation
With
sodium hydride; phosphorus trichloride;
copper(ll) sulfate pentahydrate; sodium L-ascorbate;
In
1,2-dimethoxyethane; water; ethyl acetate; tert-butyl alcohol;
