(2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

Base Information

Chemical Name:(2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate
CAS No.:853750-23-9
Molecular Formula:C₄₀H₆₂O₁₀Si
Molecular Weight:731.012
Hs Code.:

Synonyms:(2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

Suppliers and Price of (2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

There total 1 articles about (2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2R,3S)-3-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-2-[(hydroxy)(3,4-methylenedioxyphenyl)methyl]-4-butanolide

: 853750-23-9
(2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

Guidance literature:: Multi-step reaction with 2 steps

1: LiBH₄ / tetrahydrofuran / 24 h / 0 °C

2: 1.77 g / pyridine / 0.5 h / 20 °C

With pyridine; lithium borohydride; In tetrahydrofuran;
DOI:10.1039/b501151e

Reference yield: 94.0%

: 853750-23-9
(2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

: 853750-25-1
(2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-(3,4-methylenedioxybenzoyl)tetramethylene dipivaloate

Guidance literature:: With 4 A molecular sieve; pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 16h;
DOI:10.1039/b501151e

Reference yield:

: 853750-23-9
(2S,3S)-2-[(R)-(3,4-dimethoxyphenyl)(triisopropylsilyloxy)methyl]-3-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]tetramethylene dipivaloate

: 853750-32-0
(2R,3S,4S,5S)-2-(3,4-dimethoxyphenyl)-5-(3,4-methylenedioxyphenyl)-3,4-bis(pivaloyloxymethyl)tetrahydrofuran

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / PCC; 4 Angstroem molecular sieves / CH₂Cl₂ / 16 h / 20 °C

2: 87 percent / tetrabutylammonium fluoride; AcOH / tetrahydrofuran / 16 h / 20 °C

3: 79 percent / H₂ / Pd(OH)2/C / ethyl acetate / 1 h / 20 °C

With 4 A molecular sieve; tetrabutyl ammonium fluoride; hydrogen; acetic acid; pyridinium chlorochromate; palladium dihydroxide; In tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1039/b501151e