(E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate

Base Information

Chemical Name:(E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate
CAS No.:1234340-60-3
Molecular Formula:C₂₁H₂₀F₄O₃
Molecular Weight:396.382
Hs Code.:

Synonyms:(E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate

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Technology Process of (E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate

There total 2 articles about (E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1663-39-4,25232-27-3
tert-Butyl acrylate

: 911799-11-6
1,2,4,5-tetrafluoro-3-(4-methoxybenzyl)benzene

: 1234340-60-3
(E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate

Guidance literature:: With silver (II) carbonate; methyl-phenyl-thioether; palladium diacetate; In N,N-dimethyl-formamide; for 9h; diastereoselective reaction; Sealed tube; Inert atmosphere; Heating;
DOI:10.1021/ol402492s

Reference yield: 73.0%

: 1219809-73-0
(E)-tert-butyl 3-(2,3,5,6-tetrafluorophenyl)acrylate

: 824-94-2
p-methoxybenzyl chloride

: 1234340-60-3
(E)-tert-butyl 3-(2,3,5,6-tetrafluoro-4-(4-methoxybenzyl)phenyl)acrylate

Guidance literature:: With palladium diacetate; caesium carbonate; triphenylphosphine; Trimethylacetic acid; In toluene; at 140 ℃; for 12h; Inert atmosphere;
DOI:10.1039/c0cc00598c