(19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

Base Information

Chemical Name:(19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester
CAS No.:161579-77-7
Molecular Formula:C₃₁H₃₉NO₆
Molecular Weight:521.654
Hs Code.:

Synonyms:(19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

Suppliers and Price of (19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

There total 8 articles about (19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 161579-76-6
(19E,20R)-3β,20-dihydroxypregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

: 161579-77-7
(19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

Guidance literature:: With jones reagent; In acetone; for 0.333333h; Ambient temperature;
DOI:10.1016/0039-128X(94)90101-5

Reference yield:

: 74214-19-0
3β-benzoyloxy-5-bromo-6β,19-epoxy-5α-pregnan-20-one

: 161579-77-7
(19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

Guidance literature:: Multi-step reaction with 8 steps

1: 74 percent / Li(tBuO)3AlH / tetrahydrofuran / 0.5 h / 5 °C

2: 72 percent / TsOH*H₂O / 18 h / 30 °C

3: 82 percent / Zn / 2-methyl-propan-2-ol; H₂O / 1 h / Heating

4: 86 percent / Jones reagent / acetone / 0.08 h / 5 °C

5: 79 percent / pyridine / 20 h / Ambient temperature

6: 71 percent / methanol; diethyl ether

7: 73 percent / conc. HCl / CHCl₃; methanol / 18 h / 35 °C

8: 87 percent / Jones reagent / acetone / 0.33 h / Ambient temperature

With hydrogenchloride; jones reagent; toluene-4-sulfonic acid; lithium tri-t-butoxyaluminum hydride; zinc; In tetrahydrofuran; pyridine; methanol; diethyl ether; chloroform; water; acetone; tert-butyl alcohol;
DOI:10.1016/0039-128X(94)90101-5

Reference yield:

: 161579-72-2
(20R)-19-hydroxypregn-5-ene-3β,20-diyl 3-benzoate 20-formate

: 161579-77-7
(19E)-3β-hydroxy-20-oxopregn-5-en-19-al 3-benzoate 19-(O-carboxymethyl)oxime methylester

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / Jones reagent / acetone / 0.08 h / 5 °C

2: 79 percent / pyridine / 20 h / Ambient temperature

3: 71 percent / methanol; diethyl ether

4: 73 percent / conc. HCl / CHCl₃; methanol / 18 h / 35 °C

5: 87 percent / Jones reagent / acetone / 0.33 h / Ambient temperature

With hydrogenchloride; jones reagent; In pyridine; methanol; diethyl ether; chloroform; acetone;
DOI:10.1016/0039-128X(94)90101-5