4,4-difluorohexahydroazepine hydrochloride

Base Information

Chemical Name:4,4-difluorohexahydroazepine hydrochloride
CAS No.:1160721-05-0
Molecular Formula:C₆H₁₁F₂N*ClH
Molecular Weight:171.618
Hs Code.:2933998090

Synonyms:4,4-difluorohexahydroazepine hydrochloride

Suppliers and Price of 4,4-difluorohexahydroazepine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 8 raw suppliers

Chemical Property of 4,4-difluorohexahydroazepine hydrochloride

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 4,4-difluorohexahydroazepine hydrochloride

There total 2 articles about 4,4-difluorohexahydroazepine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: tert-butyl 4,4-difluoroazepane-1-carboxylate

: 1160721-05-0
4,4-difluorohexahydroazepine hydrochloride

Guidance literature:: With hydrogenchloride; In water; ethyl acetate; at 20 ℃; for 4h;

Reference yield:

: 188975-88-4
tert-butyl 4-oxoazepane-1-carboxylate

: 1160721-05-0
4,4-difluorohexahydroazepine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: [bis(2-methoxyethyl)amino]sulfur trifluoride / dichloromethane

2: acetyl chloride / methanol

With [bis(2-methoxyethyl)amino]sulfur trifluoride; acetyl chloride; In methanol; dichloromethane;

Reference yield: 37.0%

: 1160721-05-0
4,4-difluorohexahydroazepine hydrochloride

: 6-bromo-2-fluoro-3-(trifluoromethyl)benzonitrile

: C₁₄H₁₂F₆N₂

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 85 ℃; for 12h; Inert atmosphere;