2-(1,3-Thiazol-2-yl)benzoic acid

Base Information

Chemical Name:2-(1,3-Thiazol-2-yl)benzoic acid
CAS No.:927802-39-9
Molecular Formula:C₁₀H₇NO₂S
Molecular Weight:205.237
Hs Code.:
DSSTox Substance ID:DTXSID101310215

Synonyms:2-(1,3-thiazol-2-yl)benzoic acid;927802-39-9;2-(2-Thiazolyl)benzoic acid;thiazole-benzoic acid;SCHEMBL5698661;FQRCVHZNITWETI-UHFFFAOYSA-N;DTXSID101310215;2-(1,3-thiazol-2-yl)benzoicacid;AKOS040795804;DB-133334;EN300-745849

Suppliers and Price of 2-(1,3-Thiazol-2-yl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-(1,3-Thiazol-2-yl)benzoic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:205.01974964
Heavy Atom Count:14
Complexity:222

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=NC=CS2)C(=O)O

Technology Process of 2-(1,3-Thiazol-2-yl)benzoic acid

There total 4 articles about 2-(1,3-Thiazol-2-yl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl 2-(1,3-thiazol-2-yl)benzoate

: 927802-39-9
2-(1,3-thiazol-2-yl)benzoic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; methanol; at 10 - 35 ℃; for 5h;

Reference yield:

: 223575-69-7
2-(2-thiazolyl)benzaldehyde

: 927802-39-9
2-(1,3-thiazol-2-yl)benzoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; dihydrogen peroxide; In water; acetonitrile; at 15 ℃;
DOI:10.1016/j.bmc.2008.08.006

Reference yield:

: 269409-99-6
ethyl 2-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzoate

: 927802-39-9
2-(1,3-thiazol-2-yl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate / 1,2-dimethoxyethane / 80 °C / Inert atmosphere

2: sodium hydroxide; water / tetrahydrofuran; methanol / 5 h / 10 - 35 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; water; caesium carbonate; sodium hydroxide; In tetrahydrofuran; methanol; 1,2-dimethoxyethane;