2,5-Dichloro-p-xylene

Base Information

• Chemical Name: 2,5-Dichloro-p-xylene
• CAS No.: 1124-05-6
• Molecular Formula: C8H8Cl2
• Molecular Weight: 175.058
• Hs Code.: 2903999090
• European Community (EC) Number: 214-387-0
• NSC Number: 61999
• UNII: 7P8M86ZOB2
• DSSTox Substance ID: DTXSID5044780
• Nikkaji Number: J80.174G
• Wikidata: Q27268677
• ChEMBL ID: CHEMBL3185647
• Mol file: 1124-05-6.mol

Synonyms:2,5-Dichloro-p-xylene;1124-05-6;1,4-Dichloro-2,5-dimethylbenzene;2,5-Dichloro-1,4-dimethylbenzene;p-Xylene, 2,5-dichloro-;Benzene, 1,4-dichloro-2,5-dimethyl-;NSC 61999;UNII-7P8M86ZOB2;7P8M86ZOB2;DTXSID5044780;EINECS 214-387-0;MFCD00000610;NSC-61999;2,5-Dichloro-para-xylene;NSC61999;p-Xylene,5-dichloro-;NCIOpen2_003818;SCHEMBL120848;CHEMBL3185647;DTXCID3024780;2,5-Dichloro-p-xylene, 97%;Benzene,4-dichloro-2,5-dimethyl-;Tox21_301811;AC7756;1,4-Dichloro-2,5-dimethylbenzene #;AKOS004905114;AM84342;CS-W017467;NCGC00256271-01;AS-11401;SY029082;CAS-1124-05-6;D0431;FT-0602837;EN300-21130;A894591;Q-200195;Q27268677

Chemical Property of 2,5-Dichloro-p-xylene

Chemical Property:

• Vapor Pressure: 0.153mmHg at 25°C
• Melting Point: 69-70 °C
• Refractive Index: 1.538
• Boiling Point: 222.139 °C at 760 mmHg
• Flash Point: 86.084 °C
• PSA: 0.00000
• Density: 1.2 g/cm³
• LogP: 3.61020
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Sparingly), DMSO (Slightly, Heated), Hexanes (Slightly), Methanol (S
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 174.0003056
• Heavy Atom Count: 10
• Complexity: 99.8

Purity/Quality:

98% ^*data from raw suppliers

2,5-Dichloro-1,4-dimethylbenzene ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1Cl)C)Cl
• Uses: 2,5-Dichloro-1,4-dimethylbenzene can be used to produce phototropic photosensitive composition containing fluoran colorformer.

Technology Process of 2,5-Dichloro-p-xylene

There total 15 articles about 2,5-Dichloro-p-xylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.4%

para-xylene (106-42-3) → 1,4-dichloro-2,5-dimethylbenzene (1124-05-6)

Guidance literature:

With iron(III) chloride; diphenyl sulfide; at 30 - 60 ℃; for 8h; Reagent/catalyst;

Reference yield:

nitromethane (75-52-5) + para-xylene (106-42-3) → 2-chloro-1,4-dimethyl-benzene (95-72-7) + mononitro-p-xylene (89-58-7) + 1,4-dichloro-2,5-dimethylbenzene (1124-05-6)

Guidance literature:

Reference yield:

2-chloro-1,4-dimethyl-benzene (95-72-7) → 2,3-dichloro-p-xylene (34840-79-4) + 1,4-dichloro-2,5-dimethylbenzene (1124-05-6)

Guidance literature:

With chlorine; iron;

upstream raw materials:

para-xylene

2-chloro-1,4-dimethyl-benzene

2,5-dimethylbenzenesulfonic acid

4-chloro-2,5-dimethylaniline

Downstream raw materials:

1,4-dichloro-2,5-bis-dichloromethyl-benzene

1,4-dichloro-2,5-bis(dibromomethyl)benzene

2,5-dimethyl-3,6-dichloroacetophenone

3-(2,5-dichloro-4-(((2S,4S)-2-(4-cyclopropyl-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)-4-fluoropyrrolidin-1-yl)methyl)phenyl)-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)propanamide

Refernces

• 1、 -. "MANUFACTURING METHOD OF HIGH PURITY 2,5-DICHLORO-P-XYLENE". Paragraph 0024. . Retrieved 2018/03/07.
• 2、 Syvret, Robert G.,Butt, Kathleen M.,Nguyen, Tung P.,Bulleck, Victoria L.,Rieth, Ryan D.. "Novel process for generating useful electrophiles from common anions using Selectfluor fluorination agent". . p. 4487 - 4493. Retrieved 2007/10/03.