tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate

Base Information

• Chemical Name: tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate
• CAS No.: 1094106-68-9
• Molecular Formula: C₂₀H₃₁N₃O₃
• Molecular Weight: 361.484

Synonyms:tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate

Chemical Property of tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate

Chemical Property:

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Technology Process of tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate

There total 1 articles about tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H37N3O5 (1094106-67-8) → tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate (1094106-68-9)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; ethyl acetate; under 3102.97 Torr;

Reference yield:

(2E)-3-[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-prop-2-enoic acid (942316-73-6) + tert-butyl (1R,4S)-4-((S)-2-amino-3-phenylpropanamido)cyclohexylcarbamate (1094106-68-9) → (4-{(S)-2-[(E)-3-(5-chloro-2-tetrazol-1-yl-phenyl)acryloylamino]-3-phenyl-propionylamino}cyclohexyl)carbamic acid tert-butyl ester (1094106-69-0)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate;

upstream raw materials:

C₂₈H₃₇N₃O₅

Downstream raw materials:

(4-{(S)-2-[(E)-3-(5-chloro-2-tetrazol-1-yl-phenyl)acryloylamino]-3-phenyl-propionylamino}cyclohexyl)carbamic acid tert-butyl ester

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