(R)-2-(3-chloropropyl)-pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide

Base Information

Chemical Name:(R)-2-(3-chloropropyl)-pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide
CAS No.:1071837-30-3
Molecular Formula:C₁₈H₂₆ClNO₂
Molecular Weight:323.863
Hs Code.:

Synonyms:(R)-2-(3-chloropropyl)-pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-(3-chloropropyl)-pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide

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Technology Process of (R)-2-(3-chloropropyl)-pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide

There total 1 articles about (R)-2-(3-chloropropyl)-pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 6940-76-7
1-iodo-3-chloro-propane

: 637767-50-1
pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide

: 1071837-30-3
(R)-2-(3-chloropropyl)-pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide

Guidance literature:: pent-4-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenylethyl)-methylamide; With n-butyllithium; diisopropylamine; lithium chloride; In tetrahydrofuran; hexane; at -78 - 0 ℃;

1-iodo-3-chloro-propane; In tetrahydrofuran; hexane; at 0 ℃; for 1h; diastereoselective reaction;
DOI:10.1021/ol801849u