N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

Base Information

Chemical Name:N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide
CAS No.:1185281-11-1
Molecular Formula:C₂₃H₂₇N₅O₃
Molecular Weight:421.499
Hs Code.:

Synonyms:N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

Suppliers and Price of N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

There total 16 articles about N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24310-18-7
3-methyl-butyric acid hydrazide

: 1185281-06-4
N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-1H-imidazole-1-carboxamide

: 1185281-11-1
N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield:

: 409082-11-7
2-(2-methyl-5-nitrophenyl)acetonitrile

: 1185281-11-1
N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

Guidance literature:: Multi-step reaction with 7 steps

1.1: water; potassium hydroxide / methanol / 14 h / Reflux

2.1: hydrogenchloride / 1,4-dioxane / 14 h / Reflux

2.2: pH > 12

3.1: hydrogen / palladium 10% on activated carbon / ethanol / 16 h / 20 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 100 °C

5.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triphenylphosphine / 1,4-dioxane; toluene / 0.17 h / 150 °C / Microwave irradiation

6.1: acetonitrile / 2 h / 20 °C

7.1: tetrahydrofuran / 1 h / 20 °C

With hydrogenchloride; water; hydrogen; potassium carbonate; potassium hydroxide; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium 10% on activated carbon; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

: 449811-29-4
6-chloro-4-(methylamino)pyridine-3-carbaldehyde

: 1185281-11-1
N-(3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylphenyl)-2-(3-methylbutanoyl)hydrazinecarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 100 °C

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triphenylphosphine / 1,4-dioxane; toluene / 0.17 h / 150 °C / Microwave irradiation

3: acetonitrile / 2 h / 20 °C

4: tetrahydrofuran / 1 h / 20 °C

With potassium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide; toluene; acetonitrile;