N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

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Chemical Name:N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide
CAS No.:1427549-96-9
Molecular Formula:C₄₄H₄₀N₆O₈
Molecular Weight:780.837
Hs Code.:

N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

Synonyms:N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

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Chemical Property of N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

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Technology Process of N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

There total 5 articles about N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 1427549-62-9
N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-(3-hydroxyphenyl)-5-oxopyrrolidine-3-carboxamide

: 1427549-96-9
N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

Guidance literature:: With sodium carbonate; In dimethyl sulfoxide; at 20 ℃; for 24h;
DOI:10.3390/molecules171214434

Reference yield:

: 91891-24-6
N-(3-hydroxyphenyl)-2-oxopyrrolidine-4-carboxylic acid

: 1427549-96-9
N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 5 h / Reflux

2: hydrazine hydrate / isopropyl alcohol / 5 h / Reflux

3: acetic acid / isopropyl alcohol / 6 h / Reflux

4: sodium carbonate / dimethyl sulfoxide / 24 h / 20 °C

With sulfuric acid; sodium carbonate; hydrazine hydrate; acetic acid; In dimethyl sulfoxide; isopropyl alcohol;
DOI:10.3390/molecules171214434

Reference yield:

: 101626-19-1
N-(3-hydroxyphenyl)-2-oxopyrrolidine-4-carboxylic acid methyl ester

: 1427549-96-9
N-(2,5-dimethyl-1H-pyrrol-1-yl)-1-[3-({3-[3-(4-{[(2,5-dimethyl-1H-pyrrol-1-yl)amino]carbonyl}-2-oxo-1-pyrrolidinyl)phenoxy]-1,4-dioxo-1,4-dihydro-2-naphthalenyl}oxy)phenyl]-5-oxo-3-pyrrolidinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / isopropyl alcohol / 5 h / Reflux

2: acetic acid / isopropyl alcohol / 6 h / Reflux

3: sodium carbonate / dimethyl sulfoxide / 24 h / 20 °C

With sodium carbonate; hydrazine hydrate; acetic acid; In dimethyl sulfoxide; isopropyl alcohol;
DOI:10.3390/molecules171214434