p-tolylguanidine carbonate

Base Information

• Chemical Name: p-tolylguanidine carbonate
• CAS No.: 97730-69-3
• Molecular Formula: CH₂O₃*C₈H₁₁N₃
• Molecular Weight: 211.221
• Mol file: 97730-69-3.mol

Synonyms:p-tolylguanidine carbonate

Chemical Property of p-tolylguanidine carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of p-tolylguanidine carbonate

There total 3 articles about p-tolylguanidine carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-[(E)-Propylimino]-4-p-tolyl-4,5-dihydro-[1,2,4]thiadiazol-3-ylamine (129226-16-0) → n-Propyl isothiocyanate (628-30-8) + p-tolylguanidine carbonate (97730-69-3)

Guidance literature:

With sodium carbonate; In water; Heating;

Reference yield:

aminoiminomethanesulfonic acid (1184-90-3) + p-toluidine (106-49-0,12221-03-3) → p-tolylguanidine carbonate (97730-69-3)

Guidance literature:

With potassium carbonate; In ethanol; at 35 - 40 ℃; for 4h;

DOI:10.2174/157340612802084243

Reference yield:

N-propyl-N'-p-tolyl-thiourea (72529-56-7) → p-tolylguanidine carbonate (97730-69-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / conc. HCl, 6percent H₂O₂ / ethanol

2: Na₂CO₃ / H₂O / Heating

With hydrogenchloride; dihydrogen peroxide; sodium carbonate; In ethanol; water;

upstream raw materials:

5-[(E)-Propylimino]-4-p-tolyl-4,5-dihydro-[1,2,4]thiadiazol-3-ylamine

N-propyl-N'-p-tolyl-thiourea

aminoiminomethanesulfonic acid

p-toluidine

Downstream raw materials:

1-benzyl-3-thiocarbamide

3,5,6-trimethyl-N-(N-p-tolylcarbamimidoyl)pyrazine-2-carboxamide

1-(4-tolyl)guanidine

1-benzyl-3--S-benzylisothiocarbamide