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Technology Process of (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride

(3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride

Base Information
  • Chemical Name:(3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride
  • CAS No.:912-60-7
  • Molecular Formula:C22H23 N O7 . Cl H
  • Molecular Weight:449.888
  • Hs Code.:
  • European Community (EC) Number:213-014-9,811-117-9
  • NCI Thesaurus Code:C61103
  • NSC Number:757235
  • Mol file:912-60-7.mol
(3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride

Synonyms:Capval;Capval Tropfen;Embonate, Noscapine Hydrogen;Hydrochloride, Noscapine;Hydrogen Embonate, Noscapine;Librochin prikkelhoest;Narcotine;Noscapect;Noscapine;Noscapine Hydrochloride;Noscapine Hydrogen Embonate;prikkelhoest, Librochin;Tropfen, Capval;Tuscalman

Suppliers and Price of (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Noscapine hydrochloride
  • 100mg
  • $ 339.00
  • Usbiological
  • Noscapine Hydrochloride
  • 100mg
  • $ 305.00
  • TRC
  • NoscapineHydrochloride
  • 1g
  • $ 80.00
  • Tocris
  • Noscapinehydrochloride ≥99%(HPLC)
  • 100
  • $ 99.00
  • TCI Chemical
  • Noscapine Hydrochloride Hydrate >98.0%(HPLC)(T)
  • 5g
  • $ 76.00
  • Sigma-Aldrich
  • Noscapine hydrochloride hydrate analytical standard
  • 5g
  • $ 68.20
  • Sigma-Aldrich
  • Noscapine hydrochloride hydrate analytical standard
  • 25g
  • $ 269.00
  • Chem-Impex
  • Noscapinehydrochloridehydrate,98%(HPLC,T) 98%(HPLC,T)
  • 25G
  • $ 296.80
  • Chem-Impex
  • Noscapinehydrochloridehydrate,98%(HPLC,T) 98%(HPLC,T)
  • 5G
  • $ 72.80
  • Chem-Impex
  • Noscapinehydrochloridehydrate,98%(HPLC,T) 98%(HPLC,T)
  • 1G
  • $ 22.40
Total 2 raw suppliers
Chemical Property of (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride
Chemical Property:
  • Vapor Pressure:8.42E-13mmHg at 25°C 
  • Melting Point:221-223 °C(lit.) 
  • Boiling Point:565.3°Cat760mmHg 
  • Flash Point:295.7°C 
  • PSA：75.69000 
  • Density:1.332g/cm3 
  • LogP:3.62170 
  • Storage Temp.:2-8°C 
  • Solubility.:Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand. 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:8
  • Rotatable Bond Count:4
  • Exact Mass:449.1241298
  • Heavy Atom Count:31
  • Complexity:647
Purity/Quality:

98% *data from raw suppliers

Noscapine hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:Xn,Xi 
  • Statements: 22 
  • Safety Statements: 36 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl
  • Isomeric SMILES:CN1CCC2=CC3=C(C(=C2[C@@H]1[C@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl
  • Uses topical fluoroquinolone antibiotic for acne Anti-Tussive Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.
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