5-PHENYL-2-PYRIMIDINETHIOL

Base Information

• Chemical Name: 5-PHENYL-2-PYRIMIDINETHIOL
• CAS No.: 31408-19-2
• Molecular Formula: C₁₀H₈N₂S
• Molecular Weight: 188.253
• Mol file: 31408-19-2.mol

Synonyms:5-phenylpyrimidine-2(1H)-thione

Chemical Property of 5-PHENYL-2-PYRIMIDINETHIOL

Chemical Property:

Purity/Quality:

5-PHENYL-2-PYRIMIDINETHIOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-PHENYL-2-PYRIMIDINETHIOL

There total 7 articles about 5-PHENYL-2-PYRIMIDINETHIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

((E)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate (7089-34-1) + thiourea (17356-08-0) → 2-mercapto-5-phenylpyrimidine (31408-19-2)

Guidance literature:

In ethanol; 1.) room temperature, 30 min, 2.) reflux, 2 h;

DOI:10.1135/cccc19960458

Reference yield: 90.0%

((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate (7089-34-1) + thiourea (17356-08-0) → 5-phenylpyrimidine-2(1H)-thione (31408-19-2)

Guidance literature:

With sodium methylate; In methanol; ethanol; for 18.5h; Reflux;

DOI:10.1039/c4ob00094c

Reference yield: 65.0%

((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate (7089-34-1) + thiourea (17356-08-0) → 2-mercapto-5-phenylpyrimidine (31408-19-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In ethanol; for 24h; Reflux;

DOI:10.1002/jhet.3935

upstream raw materials:

3-chloro-2-phenylpropenal

thiourea

phenylacetic acid

((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate

Downstream raw materials:

(±)-3,4-dihydro-4,5-diphenylpyrimidine-2(1H)-thione

(±)-4-(3-fluorophenyl)-3,4-dihydro-5-phenylpyrimidine-2(1H)-thione

(±)-4-(6-methoxypyridin-3-yl)-5-phenyl-3,4-dihydropyrimidine-2(1H)-thione

2-(3-Butynylthio)-5-phenylpyrimidine