9(10H)-acridone carboxamide

Base Information

• Chemical Name: 9(10H)-acridone carboxamide
• CAS No.: 37760-72-8
• Molecular Formula: C14H10N2O2
• Molecular Weight: 0
• Mol file: 37760-72-8.mol

Synonyms:4-Acridinecarboxamide,9,10-dihydro-9-oxo;9-Oxo-9,10-dihydroacridine-4-carboxamide;9-oxo-9,10-dihydro-acridine-4-carboxylic acid amide;Acridon-carbonsaeure-(4)-amid;9,10-dihydro-9-oxo-4-acridinecarboxamide;9(10H)-Acridone carboxamide;

Chemical Property of 9(10H)-acridone carboxamide

Chemical Property:

• Vapor Pressure: 1.21E-07mmHg at 25°C
• Boiling Point: 431.4°C at 760 mmHg
• Flash Point: 214.7°C
• PSA: 76.94000
• Density: 1.343g/cm³
• LogP: 2.66440

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9(10H)-acridone carboxamide

There total 4 articles about 9(10H)-acridone carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

9-Oxoacridan-4-carboxylic acid (24782-64-7) → 9,10-dihydro-9-oxo-4-acridinecarboxamide (37760-72-8)

Guidance literature:

9-Oxoacridan-4-carboxylic acid; With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 10 ℃;

With ammonia; In chloroform; N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield:

9-chloro-4-aminocarbonylacridine (63178-96-1) → 9,10-dihydro-9-oxo-4-acridinecarboxamide (37760-72-8)

Guidance literature:

With hydrogenchloride; In methanol; Yield given;

Reference yield:

9-chloro-4-acridinecarbonyl chloride (89459-22-3) → 9,10-dihydro-9-oxo-4-acridinecarboxamide (37760-72-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₃ / CH₂Cl₂ / 0.5 h / Ambient temperature

2: 2N HCl / methanol

With hydrogenchloride; ammonia; In methanol; dichloromethane;

upstream raw materials:

9-chloro-4-aminocarbonylacridine

9-chloro-4-acridinecarbonyl chloride

9-Oxoacridan-4-carboxylic acid

Refernces

• 1、 Antonini, Ippolito,Martelli, Sante. "The Synthesis of a New Polycyclic Heterocyclic Ring System: Pyrimidoacridine". . p. 471 - 473. Retrieved 2007/10/02.